2024 Undergraduate Research Symposium Spring 2024 Online Proceedings (2024)

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Poster Presentation 1

11:00 AM to 12:30 PM

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Investigating the Mechanism of Toxicity Employed by the PEEL-1/ZEEL-1 Selfish Genetic Element

Presenter
  • Dora Layanto, Senior, Applied & Computational Mathematical Sciences (Biological & Life Sciences), BiochemistryMary Gates Scholar, UW Honors Program
Mentors
  • Michael Ailion, Biochemistry
  • Lews Caro, Molecular & Cellular Biology

Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Michael Ailion (1)

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    Computational Design of de novo DNA-Binding hom*odimers for Genetic Manipulation

    Presenter
    • Beau Joshua (Beau) Lonnquist, Senior, Bioengineering: Data ScienceLevinson Emerging Scholar
    Mentors
    • David Baker, Biochemistry
    • Cameron Glassco*ck, Biochemistry, Institute for Protein Design

    Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by David Baker (6)

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    Design and Optimization of a High-throughput Split-GFP Assay for Evaluating Targeted Cytoplasmic Delivery of Computationally Designed Protein-based Therapeutics

    Presenter
    • Sneha Subramanian, Senior, Public Health-Global Health
    Mentors
    • Neil King, Biochemistry
    • Justin Decarreau, Biochemistry

    Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Neil King (3)

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    Unbiased Screen on Yeast to Uncover DML1 Functions

    Presenter
    • Chloe Lani Higuchi, Senior, Biochemistry
    Mentor
    • Suzanne Hoppins, Biochemistry

    Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)

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    Effects of a rund-1 mutation on the GTPase activity of RAB-2

    Presenter
    • Daniel Christopher (Daniel) Park, Junior, Biochemistry
    Mentors
    • Michael Ailion, Biochemistry
    • Chau Vuong, Biochemistry

    Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Michael Ailion (1)

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    Specific Stimulation: Improving Vaccine Immune Response with Native Immunomodulatory Domains

    Presenter
    • Priya Christensen, Senior, Biochemistry, Public Health-Global Health
    Mentors
    • Neil King, Biochemistry
    • Marti Tooley, Biochemistry

    Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Neil King (3)

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    Rescuing PDE6 Mutation-Associated Photoreceptor Degeneration by Knocking Out IMPDH1 in Zebrafish

    Presenter
    • Riddhi Venkatasulochana Atmakuri, Senior, Public Health-Global Health
    Mentors
    • Susan Brockerhoff, Biochemistry
    • Kaitlyn Rutter, Biochemistry

    Poster Session 1

  • MGH | HUB
  • 11:00 AM to 12:30 PM
    • Other Biochemistry mentored projects (28)

    Oral Presentation 1

    11:30 AM to 1:00 PM

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    The Role of Beta-Catenin in DrosophilaMalpighian Tubule Morphogenesis

    Presenter
    • Makenna Alexis Carnahan, Junior, Biochemistry
    Mentor
    • Claudia Vasquez, Biochemistry

    Session O-1I: O-1I

  • MGH 271
  • 11:30 AM to 1:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Claudia Vasquez (1)

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    Decoding Organogenesis: Unraveling the Role of E-Cadherin in Malpighian Tubule Elongation

    Presenter
    • Megan Jane (Megan) Yi, Junior, Biochemistry
    Mentor
    • Claudia Vasquez, Biochemistry

    Session O-1I: O-1I

  • MGH 271
  • 11:30 AM to 1:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Claudia Vasquez (1)

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    Design of Toll-like Receptor 5 Mini-protein Binders for Vaccine Development

    Presenter
    • Abby Burtner, Senior, BiochemistryGoldwater Scholar, Mary Gates Scholar, UW Honors Program, Undergraduate Research Conference Travel Awardee, Washington Research Foundation Fellow
    Mentors
    • Neil King, Biochemistry
    • Chloe Adams, Biochemistry

    Session O-1I: O-1I

  • MGH 271
  • 11:30 AM to 1:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Neil King (3)

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    The Role of Shh Signaling in Dorsal-Ventral Patterning During Spinal Cord Regeneration in Xenopus tropicalis

    Presenter
    • Samuel Benjamin (Sam) Perkowski, Senior, BiochemistryMary Gates Scholar
    Mentors
    • Andrea Wills, Biochemistry
    • Avery Angell Swearer, Biochemistry

    Session O-1K: Cellular signaling and dynamics

  • MGH 231
  • 11:30 AM to 1:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Andrea Wills (1)
    • Other students mentored by Avery Angell Swearer (1)

    Poster Presentation 2

    12:45 PM to 2:00 PM

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    Investigating the Role of Tie2 Signaling in Vascular Regeneration Using Diabetic Blood Vessel Organoids

    Presenter
    • Akira Dan Morish*ta, Senior, Biology (Molecular, Cellular & Developmental)
    Mentors
    • Hannele Ruohola-Baker, Biochemistry
    • Devon Ehnes, Biochemistry
    • Yan Ting Zhao, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Hannele Ruohola-Baker (4)
    • Other students mentored by Devon Ehnes (1)

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    Investigating the Role of Cyclin E in Mitophagy-Dependent Quiescence in Drosophila Germline Stem Cells

    Presenters
    • Sahiti Peddibhotla, Senior, Biochemistry
    • Shelley Caisley, Senior, Biology (General)
    Mentors
    • Hannele Ruohola-Baker, Biochemistry
    • Tung Ching Cheryl Chan, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Hannele Ruohola-Baker (4)

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    Computational Design and E. coli-based Expression of NpRdhA Dehalogenase Protein for Bioremediation of Polychlorinated Biphenyls

    Presenters
    • Maddie Ho, Junior, Bioengineering
    • Xinyi Wang, Senior, Biology (Molecular, Cellular & Developmental)
    • Addie Lomax, Sophom*ore, Anthropology
    • Ethan Cheney, Senior, Biochemistry
    • Akira Dan Morish*ta, Senior, Biology (Molecular, Cellular & Developmental)
    Mentor
    • Frank DiMaio, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)

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    In Vivo Determination of YPT1-USO1 Binding Site

    Presenter
    • Sophina Chen, Junior, Biochemistry
    Mentors
    • Alexey Merz, Biochemistry
    • Emma Mackey, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)

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    Exploring The Role of ROS in Extracellular Vesicle Production Using Drosophila melanogaster

    Presenters
    • Leon Chen, Senior, Biology (Molecular, Cellular & Developmental)
    • Justine Lee, Senior, Biology (Molecular, Cellular & Developmental)
    Mentors
    • Young Kwon, Biochemistry
    • Annabel Vernon, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)

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    Development of a Clinically Accessible Assay for Quantifying Integrase Strand Transfer Inhibitors in HIV Treatment

    Presenter
    • Katherine Grace Buckley, Senior, Biochemistry
    Mentors
    • Jonathan Posner, Biochemistry, Bioengineering, Chemical Engineering, Mechanical Engineering
    • Andrew Bender, Mechanical Engineering

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Mechanical Engineering mentored projects (20)

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    Hetero-Oligomers of the Small Heat Shock Protein HSPB6 with HSPB1 and HSPB5

    Presenter
    • Carter Hanson, Senior, Biochemistry
    Mentors
    • Rachel Klevit, Biochemistry
    • Maria Janowska, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Rachel Klevit (1)
    • Other students mentored by Maria Janowska (1)

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    A New Model of Hydrocephalus Reveals an Unexpected Role of Hedgehog Signaling in Cell Adhesion

    Presenter
    • Lily Nguyen, Senior, Biology (Molecular, Cellular & Developmental), Biochemistry
    Mentor
    • Jennifer Kong, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Jennifer Kong (1)

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    Filament Assembly of Pseudomonas aeruginosa Glutamine Synthetase (GS)

    Presenter
    • Zeqi (Chelsea) Wang, Senior, BiochemistryMary Gates Scholar
    Mentors
    • Justin Kollman, Biochemistry
    • Richard Muniz, Biochemistry, UW-biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Justin Kollman (2)

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    Determining the Impact of Phosphorylation on Phosphoribosyl Pyrophosphate Synthetase (PRPS1) Structure and Assembly

    Presenter
    • Sophia Arons, Senior, Biochemistry
    Mentors
    • Justin Kollman, Biochemistry
    • Kelli Hvorecny, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Justin Kollman (2)

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    Electrostatic Properties of the Alpha-Crystallin Domain of HSPB5 and its Effect on Chaperone Activity

    Presenter
    • Jasleen Kaur Sidhu, Senior, BiochemistryLevinson Emerging Scholar
    Mentors
    • Rachel Klevit, Biochemistry
    • Maria Janowska, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Rachel Klevit (1)
    • Other students mentored by Maria Janowska (1)

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    Modulation of FGF Pathway Signaling and Vascular Differentiation using Design Oligomeric Assemblies

    Presenter
    • Rhea Ravi Acharya, Senior, BiochemistryUW Honors Program
    Mentors
    • Hannele Ruohola-Baker, Biochemistry
    • Ashish Phal (aphal@uw.edu)

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Hannele Ruohola-Baker (4)
    • Other students mentored by Ashish Phal (790)

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    The Role of Hedgehog Signaling on Craniofacial Development

    Presenter
    • Grace Setiawati Siauw, Senior, Pre-Sciences
    Mentor
    • Jennifer Kong, Biochemistry

    Poster Session 2

  • MGH | HUB | CSE
  • 12:45 PM to 2:00 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Jennifer Kong (1)

    Poster Presentation 3

    2:15 PM to 3:30 PM

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    Understanding Metabolic Differences Between SDH and FH Deficient Cancer Cells

    Presenter
    • Eric Zheng, Senior, Biochemistry
    Mentors
    • Lucas Sullivan, Biochemistry, UW/Fred Hutch
    • David Sokolov (sokolovd@uw.edu)

    Poster Session 3

  • MGH | HUB | CSE
  • 2:15 PM to 3:30 PM
    • Other students mentored by David Sokolov (790)

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    Quantifying Functional Neuron Regeneration After Xenopus tropicalisTadpole Spinal Cord Amputation

    Presenter
    • Iba Husain, Junior, Pre-Sciences
    Mentors
    • Andrea Wills, Biochemistry
    • Avery Angell Swearer, Biochemistry

    Poster Session 3

  • MGH | HUB | CSE
  • 2:15 PM to 3:30 PM
    • Other Biochemistry mentored projects (28)
    • Other students mentored by Andrea Wills (1)
    • Other students mentored by Avery Angell Swearer (1)

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    Investigating the Monomer-dimer Equlibrium of the Dam1 Complex from Yeast with Human Histones

    Presenter
    • Emmanuel Boakye-Ansah, Senior, Psychology, Biochemistry
    Mentor
    • Trisha Davis, Biochemistry

    Poster Session 3

  • MGH | HUB | CSE
  • 2:15 PM to 3:30 PM

    • Oral Presentation 3

      3:30 PM to 5:00 PM

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      Deep Learning-Based Design of Heterooligomeric Icosahedral Protein Nanoparticles

      Presenter
      • Ethan Eschbach, Senior, Chemical Engineering
      Mentors
      • Neil King, Biochemistry
      • Helen Eisenach, Biochemistry

      Session O-3N: O-3N

    • CSE 691
    • 3:30 PM to 5:00 PM
      • Other Biochemistry mentored projects (28)
      • Other students mentored by Neil King (3)

      2024 Undergraduate Research Symposium Spring 2024 Online Proceedings (2024)

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